Testicular Metastasis from Adenocarcinoma of the Prostate: Review of Literature and Report of Two Cases

Tumor metastases to the testes, excluding lymphomas and leukemias, are extremely uncommon. In the literature there have been reports of 236 different cancer metastases to the testis. The most common origin is the prostate in 76 (32%) cases. We report two additional cases of testicular metastases from adenocarcinoma of the prostate. Immunohistochemical analysis of prostate specific antigen indicated that the metastatic cancer was of prostatic origin.