Role of free testosterone serum levels during salvage chemotherapy with carboplatin plus weekly docetaxel in patients with docetaxel-refractory, metastatic castration-resistant prostate cancer (mCRPC).

Stefan Brunotte,Philipp Ivanyi,Paula Kappler,Michael A. Morgan,Christoph Reuter

Role of free testosterone serum levels during salvage chemotherapy with carboplatin plus weekly docetaxel in patients with docetaxel-refractory, metastatic castration-resistant prostate cancer (mCRPC).

2021

Stefan Brunotte
Philipp Ivanyi
Paula Kappler
Michael A. Morgan
Christoph Reuter

145Background: Carboplatin plus docetaxel (CD) may be effective in mDRPC. Platinum(II)-complexes interfere with steroid biosynthesis and thus lower testosterone levels. In this study, the impact of...

Keywords:

Prostate cancer
Oncology
Docetaxel
castration resistant
Refractory
Testosterone
steroid biosynthesis
Carboplatin
Free testosterone
Internal medicine
Medicine

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