Comment on Impaired Priming and Activation of the Neutrophil NADPH Oxidase in Patients with IRAK4 or NEMO Deficiency

We have read with interest the article published by Singh et al. in the May 4, 2009 issue of The Journal of Immunology ([1][1]). NF-κB is an essential transcription factor for multiple genes related to the immune response and development ([2][2], [3][3]). Previous studies by our group and others