Abstract 19203: A Case of New Supraventricular Tachycardia During Pregnancy, With the Development of Post-partum Eclampsia, Torsades De Pointes, and Long Qt Syndrome: Is There a Connection?

Background: There is a mechanistic link between QT prolongation and the development of TdP. Women with LQTS have an increased risk of serious cardiac arrhythmias during the postpartum period,however,there is limited data on the effects of pregnancy on those without a prolonged QT prior to delivery. Case Description: The patient is a 22 y/o female with no history of arrhythmia.During pregnancy she had three episodes of SVT,each prompting hospital admissions.ECG showed a heart rate of 148-163bpm,a QTc of 390 to 410ms,and laboratory data a magnesium level of 1.6.On day 3 after a scheduled cesarean section, she suffered a eclamptic seizure and then a Tdp induced cardiac arrest.Magnesium was immediately given.CPR was performed for 31 minutes until return of spontaneous circulation was achieved.The patient had an extended ICU course but was eventually discharged home with her newborn twins,a subcutaneous implantable cardiac defibrillator (S-ICD),multiple postpartum ECGs showing QTc of 493 to 524ms,and a diagnos...