Measles Vaccine Field Trials in Alaska

Live measles vaccine was given to almost the entire population of the village of St. Paul in the Pribilof Islands in 1963, where exposure to measles had not occurred since 1942. Reactions among susceptibles tended to be mild, with temperatures of 102 F (38.9 C) or over occurring in 7%, and rash appearing in 6% of 164 individuals. No clinical or serologic response was noted among seroimmune individuals when vaccine was administered with or without \g=g\-globulin.