Evaluation of a novel Scheimpflug-based non-contact tonometer in healthy subjects and patients with ocular hypertension and glaucoma

Background To evaluate the agreement of intraocular pressure (IOP) and central corneal thickness (CCT) measurements obtained with the non-contact tonometer Corvis Scheimpflug Technology (Corvis ST, OCULUS, Wetzlar, Germany) versus Goldmann applanation tonometry (GAT) and ultrasound-based corneal pachymetry (US-CCT). Methods Eye healthy participants, patients with ocular hypertension (OHT) and patients with open-angle glaucoma were included in this prospective study. In each participant, GAT, US-CCT and measurements with Corvis ST were obtained (Corvis-IOP and Corvis-CCT). Accuracy and repeatability were tested by correlation and regression analyses, Bland-Altman plots and assessment of intraclass correlation coefficients. Results A consecutive series of 188 right study eyes of 188 participants (142 eyes with glaucoma, 10 eyes with OHT and 36 control eyes) were included in this prospective study. The mean GAT of all included was 14.5±4.8 mm Hg compared with mean Corvis-IOP of 15.4±5.6 mm Hg (Spearman’s r=0.75, p Conclusions Obtaining CCT and measuring IOP with the Corvis ST reveals very good repeatability and good accuracy in healthy subjects and patients with OHT and glaucoma when compared with standardised US pachymetry or GAT.