Пациенты с сердечно-сосудистыми заболеваниями и прием НПВП: реальная клиническая практика

Objective — to study the frequency and characteristics of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with cardiovascular diseases hospitalized in the emergency departments of cardiology. Materials and methods . Examined 190 patients hospitalized in the emergency cardiology departments of the State Healthcare Institution Regional Clinical Hospital of Saratov from January to March 2020. The study was continuous, a questionnaire was conducted for all patients hospitalized during the specified period. The study involved 103 (54%) men and 87 women, the average age of the patients was 62.05 ± 11.11 years. The reason for hospitalization in most patients was acute coronary pathology — 116 (61%) patients, 34 (18%) patients — decompensated heart failure, 21 (11%) patients — various rhythm disturbances; in 15 (8%) patients — hypertensive crisis against the background of uncontrolled arterial hypertension, in 4 (2%) patients — pulmonary embolism. Results . During the last month, 92 (48%) patients took NSAIDs for various reasons: 42 men (46%) and 50 women (54%). The average age of patients taking NSAIDs is higher than that of patients who did not take NSAIDs (63.98 ± 11.62 years and 60.20 ± 10.27 years, respectively, p = 0.018). Among patients forced to take NSAIDs over the past month, joint pain — 43 (47%) patients, headache — 40 (43%) patients, back pain — 30 (33%) were indicated as the main cause or one of the reasons sick. In 15 (16%) patients, the reason for taking NSAIDs was toothache, in 14 (15%) patients — chest pain, musculoskeletal pain — in 11 patients (12%). Several reasons for taking NSAIDs were indicated by 40 (43%) patients, the majority — a combination of joint pain and back pain. Conclusion . Almost half of patients admitted to emergency cardiology departments had taken NSAIDs in the previous month. Most patients have to take NSAIDs often, regularly, for a long time. More than a third of the examined patients used various methods of drug administration, including unreasonably frequent and prolonged parenteral use or the simultaneous use of various methods of administration of various drugs.