MUC1 Aptamer-Based Near-Infrared Fluorescence Probes for Tumor Imaging

Juan Zhao,Yuxiang Ma,Sisi Cui,Jie Cao,Samuel Achilefu,Yueqing Gu

MUC1 Aptamer-Based Near-Infrared Fluorescence Probes for Tumor Imaging

2013

Juan Zhao
Yuxiang Ma
Sisi Cui
Jie Cao
Samuel Achilefu
Yueqing Gu

Purpose DNA aptamer (APT) is able to bind to Mucin 1 (MUC1) specifically. The possibility of APT acting as a moiety to construct tumor-targeting probes was investigated.

Keywords:

Medical physics
Moiety
MUC1
Optics
Aptamer
Fluorescence
Molecular biology
Physics
Ovarian cancer
Systematic evolution of ligands by exponential enrichment
Cell
Cell culture
Mucin

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