Synthesis of 2-Benzylphenyl Ketones by Aryne Insertion into Unactivated C–C Bonds

A transition-metal-free procedure to access to functionalized 2-benzylphenyl ketones is described by direct insertion of arynes into benzylic C–C bonds. This reaction was promoted by cesium fluoride at room temperature, allowing the products to form in high selectivity and achieve good functional group tolerance.