FRI0104 Reactive arthritis in 43 iranian patients

Background Reactive arthritis refers to an acute non-purulent arthritis reactive to an infection elsewhere in the body. Objectives The aim of this study was to find the demography of reactive arthritis in Iranian patients. Methods In a five years period 43 patients who definitely were diagnosed as Reactive Arthritis were seen in our centre. All patients were classified by the European Criteria for reactive arthritis classification. 139 items were checked in every patient. The data were analysed by SPSS software. Results The age ratio was 17–45 years with a mean age of 23.8 years. Forty patients (93%) were male and the male to female ratio was 13/1. A history of infection in 1 to 4 weeks before the attack of reactive arthritis was diarrhoea in 20 (46.5%) and urethritis in 16 patients (37.2%). The clinical manifestation during the disease were: constitutional symptoms in 24 (55.8%), including fever 44.2%, weight loss 32.6%, fatigue 20.9%, lower extremity arthritis 100%, and upper extremity arthritis 48.8%. Sacroiliac involvement was seen in 37.2% of patients. The most common peripheral arthritis was seen in ankle (83.7%) and knee joints (76.7%). Achilles and Calcaneal Enthesopathy were seen in 46.5% of patients. Extra articular manifestations were seen in 37 patients (86%): eye involvement in 31 patients (55.8%) and mucocutaneous involvement in 13 patients (30.2%). Lab test: Leucocytosis were seen in 23.2%, Anaemia in 11.7%, Erythrocyte sedimentation rate > 50 in 62.5%, positive CRP in 83.7% and positive HLA-B27 in 46.8% of cases. Conclusion Reactive Arthritis in Iranian patients has the same clinical manifestations as in other countries. Male to female ratio in the Iranian patient is more than in other countries. HLA-B27 is less common in Iranian patients than in other countries.