32 Replication stress is a determinant of synergy between gemcitabine and Chk1 inhibition

R. Dornetshuber-Fleiss, P. Heffeter, T. Mohr, P. Hazemi, K. Kryeziu, C. Seger, W. Berger, R. Lemmens-Gruber. University of Vienna and Medical University of Vienna, Institute of Pharmacology and Toxicology and the Institute of Cancer Research Department of Medicine I and Comprehensive Cancer Center of the Medical University, Vienna, Austria; Medical University of Vienna, Institute of Cancer Research Department of Medicine I and Comprehensive Cancer Center of the Medical University, Vienna, Austria; University of Vienna, Department of Pharmacology and Toxicology, Vienna, Austria; Medical University of Vienna, Institute of Cancer Research Department of Medicine I and Comprehensive Cancer Center of the Medical University, Vienna, Austria; Leopold-Franzens University Innsbruck, Institute of Pharmacy Department of Pharmacognosy, Vienna, Austria