AN OPERATED CASE OF WERNER'S SYNDROME WITH AORTIC ARCH SYNDROME

A 41-year-old man was admitted to the hospital because of double vision. He was short of stature and the hair was white. His voice was high tone and hoarsely. Tylosis like skin lesion and hypospadias were found. There was a previous history of undergoing an operation for cataract. Dysbolism of glucose and fatty liver were confirmed. The patient was diagnosed as Werner's syndrome. Angiography revealed strictures of the bilateral carotid arteries, stricture of the left subclavian artery, and complete occlusion of the left external carotid artery. The coronary artery was normal. A diagnosis of aortic arch syndrome with transient cerebral ischemia was made. This case was determined to be a possible candidate for vascular reconstruction of the cranial portion of external carotid artery. After thromboendarterectomy for the stenosed portion of the left subclavian artery, by using the same portion and greater saphenous vein, a bypass operation was performed at the left internal carotid artery. Postoperative course was uneventful. Some characteristic findings were obtained by cultivation of the abdominal skin. This is the first case of vascular reconstruction of the cranial portion of external carotid artery for this syndrome in this country. Since the disease presents a rapid progress of arteriosclerosis due to its peculiarity, strict observation of the clinical course would be mandatory.