Anti-depression effect and mechanism of Suanzaoren Decoction on mice with depression

Objective: To study the therapeutic effect and mechanism of Suanzaoren Decoction on mice with depression. Methods: A model of depression was prepared by chronic unpredictable stimulation and reserpine induction. Behavioral tests, determination of norepinephrine and dopamine were performed. Results: The behavioral indicators of the model group were reduced, and the expression of norepinephrine and dopamine was decreased. Conclusion: Suanzaoren Decoction has an effect on the increase of serum norepinephrine and dopamine content, indicating that the jujube seed Soup has a certain effect on depression.