Sonographisch gezielte Stanzbiopsie: Wie viele Biopsiezylinder sind notwendig?

Purpose: To determine the optimum number of specimens of a sonographically guided core biopsy of the breast. Materials and Methods: From January 2001 to April 2001, sonographically guided core biopsies (coaxial needle: 11 G; core needle: 12 G) were performed on 106 patients with 115 BI-RADS 4-5 lesions that had corresponding sonographic findings. Five specimens were obtained in anteroposterior direction parallel to the chest wall and each specimen examined histologically. Results: A total of 575 core biopsies produced 545 specimens (94.8%), with no material obtained in 30 biopsies (5.2%). The first and second specimen confirmed the diagnosis in 99 of 115 lesions (86%), with subsequent specimens confirming the diagnosis in 87% (3 rd specimen), 88% (4 th specimen) and 82% (5 th specimen). The additive accuracy of the five core breast specimens was 86%, 96%, 98%, 99% and 100%. The possible volume of 78.9 mm 3 as determined by the sample notch of the core needle only furnished an average volume of 38.1 mm 3 (41.1 mm 3 for the 1 st , 40.1 mm 3 for the 2 nd , 37.5 mm 3 for the 3 rd , 36.7 mm 3 for the 4 th and 35.0 mm 3 for 5 th core specimen). Conclusion: Sonographically guided core breast biopsy (coaxial needle: 11 G; core needle: 12 G) may require five passes to achieve a diagnostic accuracy of more than 99%.