Low Incidence of Colorectal Cancer in Kerman Province, Iran

Background: In Iran colorectal cancer (CRC) incidence varies among various places. But we do not have any validate data that deeply explored the difference of CRC in Kerman province by national average. The aim of this study was to evaluate the incidence of colon cancer within a 12-year period in Kerman province and to find whether the incidence of CRC in Kerman compared with the total incidence found in Iran. Methods: Data on colorectal cancer was collected from all histopathology departments around the Kerman Province during 1991 – 2002 retrospectively. The crude and age-standardized incidence rates per 1 million populations were calculated based on the 1996 census data and the population growth rate. Results: During this study total number of 551 new cases of colorectal cancer in Kerman province had been diagnosed. Age Standardized Rate of colon cancer in males and females were 50 (95% CI: 44-56) and 53 (95% CI: 46-59) cases per 1,000,000 population per year, respectively. The risk ratio in females relative to males was not significant in any type of colon cancer. We did not find any difference for each year during the entire study period. Conclusion: The ASR of colorectal cancer in Kerman province was quite lower than the average rate in the whole country. This study showed that, the risk of acquiring colon cancer was constant. We concluded that the risk of colorectal cancer in Kerman province was much lower than the entire country. Keywords: Neoplasm; Iran; Trend analysis, Epidemiology, Colorectal Please cite this article as: Haghdoost AA, Chamani G, Zarei MR, Rad M, Hashemipoor M, Marzban M. Low Incidence of Colorectal Cancer in Kerman Province, Iran. Iran J Cancer Prev.2011; Vol4, No1, P.33-37. References 1. Boyle P, Leon ME. Epidemiology of colorectal cancer. British medical bulletin. 2002; 64(1):1. 2. Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2002: cancer incidence, mortality and prevalence worldwide. IARC cancerbase. 2004; 5:2.0. 3. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA: a cancer journal for clinicians. 2005; 55(2):74. 4. Boyle P, Langman JS. ABC of colorectal cancer: Epidemiology. British Medical Journal. 2000; 321 (7264): 805. 5. Cancer Trends Progress Report (http:// progressreport. cancer.gov) id, based on methods described in Medical Care 2002 Aug; 40(8 Suppl): IV-104–17. 6. ENCR. European Network of Cancer Registries. Eurocim. 1999; V2.2 (1999). Lyon; 2001. 7. Reporting of cancer registry for 2005. Cancer registry center, Ministry of Health and Medical Education. 2007; 1: XXVIII. 8. Mousavi SM, Gouya MM, Ramazani R, Davanlou M, Hajsadeghi N, Seddighi Z. Cancer incidence and mortality in Iran. Annals of Oncology. 2009; 20(3):556. 9. Malekzadeh R, Bishehsari F, Mahdavinia M, Ansari R. Epidemiology and molecular genetics of colorectal cancer in iran: a review. Archives of Iranian Medicine. 2009; 12(2):161-9. 10. Zarei MR, Chamani G, Hashemipoor MS, Rad M, Haghdoost A. An Epidemiologic study of Oral and Pharyngeal Nonsquamous Cell Malignant Tumors in Kerman province, Iran. Journal of Dentistry of Tehran University of Medical Sciences. 2007; 4(1):37-43. 11. Haghdoost AA, Hosseini H, Chamani G, Zarei MR, Rad M, Hashemipoor M, et al. Rising incidence of adenocarcinoma of the esophagus in Kerman, Iran. Arch Iran Med. 2008; 11(4):364-70. 12. Mossavi sM. Reporting of cancer registry center. Ministry of Health and Medical Education,  2004-2006. 13. Nyren O, AH-OSCIAH-O, Hunter D, Trichopoulos D. Textbook of Cancer Epidemiology. New York: Oxford University Press; 2008. 14. Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, Kearney J, et al. A prospective study of cigarette smoking and risk of colorectal adenoma and colorectal cancer in US men. JNCI Journal of the National Cancer Institute. 1994; 86(3):183. 15. Potter JD. Nutrition and colorectal cancer. Cancer Causes and Control. 1996; 7(1):127-46. 16. Ardeshir KH ,Najafi  F, Rahbar MR, Esmail Motlagh M,  Kabi M. Indexes of health system in Islamic Republic of Iran. Ministry of Health and Medical Education. 2007; 1.