Progress on follicular fluid metabolomics

The exploration and discovery of biomarkers that can successfully predict oocyte quality is one of the key factors to improve the success rate of human assisted reproductive technology (ART). After the emergence of morphological, genomic and proteomic studies, metabolomics rise as one of the most promising methods to search for the prediction of oocyte quality in follicular fluid. Metabolomics has recently become an immediate areas of research focus with its objectivity, accuracy, less varieties of metabolites, and relatively simple measurement. This paper reviews the research progess of follicular fluid metabolismics which is a field worthy of research. Key words: Metabolomics; Oocyte; Follicular fluid; Biomarkers