Sister Mary Joseph nodule

1A 64-year-old female presented with a three-month history of decreased appetite, nausea and progressive abdominal distension. Physical examination revealed a distended abdomen with a fluid wave and a hard perium bilical bluish swelling (Fig. A). Because intra-abdominal malignancy was suspected, a contrastenhanced computed tomography of the abdomen was performed which showed a pelvic mass originating from the left ovary, omental and peritoneal metastases, ascites, and a lobulated mass through the umbilicus with infiltration of the surrounding subcutaneous fat (Fig. B, C). Diagnostic laparoscopy and histopathological analysis of the obtained ovarian samples confirmed the diagnosis of metastatic ovarian carcinoma. A Sister Mary Joseph nodule (SMJN) is a metastatic umbilical lesion originating from intra-abdominal or pelvic malignant disease. It can be a sign of undiagnosed malignancy or a symptom or sign of disease progression or recurrence in a patient with known disease. Its incidence is low,