In Vitro Antibacterial and Antifungal Activities of Some Sulfur–Nitrogen–Oxygen and Oxygen–Nitrogen–Oxygen Donor Bifunctional Tridentate Schiff Bases and Their Boron(III) Complexes

Antimicrobial properties of sulfur, nitrogen, and oxygen bonded organoboron (III) complexes with biologically potent ligands viz., 2-hydroxy-N-phenyl benzamide hydrazine carboxamide(HO∩N∩OH), 2-hydroxy-N-phenyl benzamide hydrazine carbothioamide (HO∩N∩SH), and 2-hydroxy-N-phenyl benzamide hydrazine carbodithioic acid (HO∩N∩SH), have been studied. The unimolar and bimolar reactions of triisopropoxy borane with dibasic tridentate ligands resulted in the formation of colored solids, which have been characterized by elemental analysis, molecular weight determinations, and conductance measurements. The UV, IR, and NMR (1H, 13C, and 11B) spectral studies indicate a tetra-coordinated geometry for the resulting complexes. The ligands and their complexes have been screened for their fungicidal and bactericidal activities, and the results indicate that they exhibit significant antimicrobial properties. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur,...