Myocardial Kinetics of a Novel [18F]-Labeled Sympathetic Nerve PET Tracer LMI1195 in the Isolated Perfused Rabbit Heart

A radionuclide tracer approach is a unique assay to monitor the cardiac sympathetic nervous system in patients, and the most widely available tracer is the radiolabeled norepinephrine analogue [123I]-metaiodobenzylguanidine ([123I]-MIBG). A novel 18F-labeled positron emission tomography (PET)