Bacterial Distribution and Analysis of Drug Resistance in Intensive Care Unit

OBJECTIVE To investigate the bacterial distribution and resistance in ICU infections,and provide basis for clinicals to select antibiotics rationally.METHODS A total of 807 bacteria strains isolated from ICU were identified and tested the drug sensitivity.The results were analyzed using WHONET 5.4 software.RESULTS Of the 807 bacteria strains isolated,77.2% were Gram-negative bacteria and 15.7% were Gram-positive bacteria.Non-fermentatives were the main species in Gram-negative bacteria.ESBLs positive rates of Echerichia coli and Klebsiella pneumoniae were 33.9% and 25.9%,respectively.Gram-positive bacteria were Staphylococcus aureus and coagulase-negative Staphylococcus and Enterococcus mainly.meticillin-resistant S.aureus(MRSA) and meticillin-resistant coagulase-negative Staphylococcus(MRCNS) were 56.9% and 70.7%,respectively.No Staphylococcus strain was resistant to vancomycin.CONCLUSIONS We should enhance the management of infection and the monitoring of bacterial resistance in ICU in order to reduce the infection rate in hospital and the resistance rate of bacteria.