Management of Reactions and Complications Following Radiation Therapy

Solum dosis fecit venerium. This adage is of significant relevance for radiation-specific toxicity. For both individual doses and the total dosage, the irradiation time frame and the irradiation volume are the most important parameters in clinical practice for comparing the tumoricidal dose with the tolerance dose of normal tissue (Fletcher 1979; Seegenschmiedt and Sauer 1993).