Impact of sex on management and survival in aortic stenosis

Aims Increasing attention has been paid to sex differences in recent studies, but only a few have focused on such differences in aortic stenosis (AS). We sought to evaluate the differences between genders in AS outcomes and management. Methods and results We included 2429 patients(51.5% men; 49.5% women) with severe AS. Women were olde r(P  Fig. 1 ). Conclusion Women with severe AS present at a more advance stage of the disease, at older ages with more symptoms, and incur higher mortality than men. This excess mortality is related to a combination of late diagnosis and a less frequent and later referral for AVR than in men. This justifies appropriate measures to improve the situation and to ensure that both sexes receive equivalent care.