Abstract 163: NFkB Promotes Oxidative Stress-induced Necrosis and Ischemia Reperfusion Injury Through NRF2-ARE Pathway

Objective: Despite the well-studied pro-survival function of nuclear factor-κB (NFκB), recent studies suggest that NFκB may also play a pathogenic role in myocardial ischemia injury and adverse remodeling. This study aims to define a new pro-cell death role of NFκB in response to oxidative stress an