Concentrations of Isotretinoin and the Arotinoid Ro 15-0778 in Plasma and Tissues of Hamsters and Rats

Floie M. Vane,Sarita S. Chari,James F. Hurley,Stanley S. Shapiro

Concentrations of Isotretinoin and the Arotinoid Ro 15-0778 in Plasma and Tissues of Hamsters and Rats

1988

Floie M. Vane
Sarita S. Chari
James F. Hurley
Stanley S. Shapiro

The arotinoid Ro 15-0778 is a potent inhibitor of sebum secretion in rodents but not in humans, while isotretinoin (13- cis -retinoic acid, Accutane®) inhibits sebum secretion in rode

Keywords:

Biochemistry
Acne
Sebum secretion
Isotretinoin
Metabolism
Retinoid
Diabetes mellitus
Biology
Internal medicine
Endocrinology
Retinoic acid
plasma concentration

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