Histopathological Study of Brain from Cattle with Nervous Symptomatology

Abstract This study aim the identification of morphopatological changes of the central nervous system in cattle with clinical nervous symptoms. Studied animals were represented by brain samples from cattle with clinical nervous signs, received in the Morphopathology Department for diagnosis of TSEs and other neurological diseases. Application of diagnostic protocol for cattle with nervous symptoms is according to the diagram flow of the Manual of diagnostic for transmissible spongiform encephalopathies target category “live bovine, animals slaughtered or dead animals with showed clinical nervous signs, behavioral changes and that during 15 days clinical observation (according to clinical observation sheet) did not respond to treatment, the evolution of disease resulting in worsening progressively.” Were performed specific laboratory tests for diagnosis confirmation in this respect: rapid tests and confirmatory tests for BSE, virusological investigations for rabies and Aujeszky’ disease and bacteriological investigations for listeriosis. Were also carried out histological investigation of brain samples for highlight topohystopathological / patognomonic changes.