Acute and subchronic toxicity study of Tamra Bhasma (incinerated copper) prepared with and without Amritikarana

Background Tamra Bhasma (TB) is one among herbo-metallic preparations extensively used in routine ayurvedic practice. In the present era, Bhasma preparations used in ayurvedic system of medicines are always under stern observations for containing heavy metals which may raise the question of safety aspect.