A RANDOMIZED PROSPECTIVE TRIAL OF INTRARECTAL LIDOCAINE FOR PAIN CONTROL DURING TRANSRECTAL PROSTATE BIOPSY: THE EMORY UNIVERSITY EXPERIENCE

Purpose: We prospectively evaluated the safety and efficacy of intrarectal lidocaine gel as anesthesia during transrectal prostate biopsy.Materials and Methods: Of 63 consecutive men undergoing transrectal prostate biopsy 50 who qualified were enrolled in this study. Indications for the procedure were an abnormal prostate on digital rectal examination and/or elevated serum prostate specific antigen. Patients were randomized into group 1—25 who received 10 cc of 2% intrarectal lidocaine 10 minutes before the procedure and group 2—25 controls. No narcotics, sedation or analgesia was given. Pain during biopsy was assessed using a 10-point linear visual analog pain scale.Results: In groups 1 and 2 median patient age was 63 and 66 years (p = 0.139), and median prostate specific antigen was 6.04 (range 1.07 to 263) and 7.24 (range 1.34 to 51.82) ng./ml. (p = 0.337). Digital rectal examination was normal and abnormal in 17 and 15 group 1, and in 8 and 10 group 2 patients, respectively. Ultrasound showed a median...