Diagnóstico prénatal: retrospectiva

Prenatal diagnosis is a set of techniques intended to establish a fetal diagnosis even in the period of intrauterine life. It is aimed primarily at couples with higher risk of having a genetic or congenital abnormal pregnancy. Its basic aim is to ensure the identification of chromosomal anomalies, malformations, metabolic and Mendelian diseases, and other alterations eventually acquired during pregnancy which have an impact on the fetus.Prenatal diagnosis has been used as a formal diagnosis method for more than 45 years, going through the various stages of its evolution. This text revises these phases by addressing the scientific and technological developments that have led to its implementation and continuous improvement.