FLUOROTHERMOPLASTIC CHIPS FOR DROPLET MICROFLUIDICS AND DNA ANALYSIS

We present a fabrication technique allowing the production of monolithic fluorinated microfluidic chips. We used an new material (Dyneon THV), compatible with fluorinated oils and organic solvents. Microfeatures are produced by hot embossing using flexible molds, and chips are sealed by a new bonding technique based on the use of two different grades of the polymer. We developed a new strategy to obtain round channels, by bonding two blocks containing hemicircular structures. Bonding was possible by selective transfer of the adhesive layer and alignment was obtained by putting cylindrical spacers in unconnected extra-channels.