Association of polymorphisms in LEPR with type 2 diabetes and related metabolic traits in a Chinese population

Lulu Zhang,Yingfen Qin,Danyan Liang,Li Li,Yaojie Liang,Lulin Chen,Lei Tong,Jia Zhou,Hong Li,Haiying Zhang

Association of polymorphisms in LEPR with type 2 diabetes and related metabolic traits in a Chinese population

2018

Lulu Zhang
Yingfen Qin
Danyan Liang
Li Li
Yaojie Liang
Lulin Chen
Lei Tong
Jia Zhou
Hong Li
Haiying Zhang

Background Leptin acts as a mediator of inflammation and energy homeostasis by activating leptin receptor (LEPR). We conducted this study to explore the association of polymorphisms in LEPR with type 2 diabetes mellitus (T2DM) and its related metabolic traits.

Keywords:

Endocrinology
Polymorphism (computer science)
Type 2 Diabetes Mellitus
Diabetes mellitus
Internal medicine
Leptin
Biology
Energy homeostasis
Population
Type 2 diabetes
Leptin receptor
Allele
Allele frequency

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