A Facile Synthetic Approach to Labeled 4-Acetoxy-2-(4-methylphenyl) benzothiazole.
1996
To study the pharmacokinetics and metabolism of 4-acetoxy-2-(4-methylphenyl)benzothiazole (KB-2683), which has potential immunomodulating activity, a practical preparation of labeled KB-2683 was needed. This paper describes an efficient method for the synthesis of 14C-labeled KB-2683 by means of procedures which include a metal-catalyzed cross-coupling reaction.
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