Quercetin and resveratrol, aging and kidney

Abstract Different environmental and genetic factors contribute to the process of aging as the ultimate cause of structural and physiological changes in body organs. Diabetes, with an increasing prevalence worldwide, is a progressive metabolic disease contributing to the acceleration of aging process. Diabetes damages the kidney through different mechanisms of inflammation, oxidative stress, and the basement membrane thickening and will turn into kidney failure if it is not properly managed. One management strategy in diabetes is the use of plants polyphenols. Resveratrol is a polyphenol compound that is useful in ameliorating diabetes-mediated oxidative stress and aging. This chapter aimed to increase researcher focus on diabetes as a facilitating agent to kidney tissue and cell aging and also management strategies.