Familial Adenomatous Polyposis

Familial adenomatous polyposis FAP is autosomal dominant inherited disorder Usually there are more than polyps All can develop carcinoma of the colon if not treated Median life expectancy is years in untreated and this can be extended greatly if colectomy is performed Causes of death after colectomy are upper GI cancers and desmoids Family members should be informed about screening Carcinoma surveillance is essential after colectomy