Endotoxin reduction using disposable adsorption technology in in cGMP manufacturing

The bioprocessing Industry Is increasing its use of membrane chromatography technology, especially for contaminant removal. The high flow rates, ease of use, disposability, and relatively low cost make it ideal for polishing applications. In a case study from Avecia Biotechnology, UK, the Sartobind Q (Sartorius) membrane chromatography product was used to remove endotoxin from a process stream. The result demonstrated advantages In time, product recovery, and cost over a traditional column step, leading to its use in a cGMP manufacturing process.