Lb3.257 Estimating progress towards elimination of congenital syphilis in south africa: incidence trends using centralised laboratory data, 2010–2015

Introduction The elimination target for congenital syphilis (CS) is Methods We conducted a cross-sectional analysis of laboratory data collected through the National Health Laboratory Service (NHLS) Corporate Data Warehouse (CDW) from 2010 to 2015. The NHLS CDW is a central repository of all laboratory tests performed in all public sector clinical laboratories in South Africa. We defined possible early CS as a positive serum Rapid Plasma Reagen (RPR) result in a child Results Of 84 341 Conclusion Though limited to laboratory results, the analysis shows high incidence possible CS. SA may need to intensify elimination efforts to reach the WHO target. Further clinical and maternal treatment information is needed in order to confirm incidence rates of early CS.