Liquid biopsy of the immune environment: Evaluation of peripheral blood mononuclear cells (PBMCs) with CyTOF and response to trastuzumab (T)-based neoadjuvant chemotherapy (NAC) in HER2+ breast cancer (BC).

Roberto A. Leon-Ferre,Kaitlyn McGrath,Vera J. Suman,Jodi M. Carter,Krishna R Kalari,Richard M Weinshilboum,Liewei Wang,James N. Ingle,Keith L. Knutson,Stephen M. Ansell,Judy C. Boughey,Jose C. Villasboas,Matthew P. Goetz

Liquid biopsy of the immune environment: Evaluation of peripheral blood mononuclear cells (PBMCs) with CyTOF and response to trastuzumab (T)-based neoadjuvant chemotherapy (NAC) in HER2+ breast cancer (BC).

2020

Roberto A. Leon-Ferre
Kaitlyn McGrath
Vera J. Suman
Jodi M. Carter
Krishna R Kalari
Richard M Weinshilboum
Liewei Wang
James N. Ingle
Keith L. Knutson
Stephen M. Ansell
Judy C. Boughey
Jose C. Villasboas
Matthew P. Goetz

592Background: Immune responses in the tumor microenvironment have prognostic and predictive value in BC. However, the potential of immune responses observed in peripheral blood as biomarkers in BC...

Keywords:

Liquid biopsy
Trastuzumab
Immune system
Chemotherapy
Biomarker (medicine)
Breast cancer
Tumor microenvironment
Pathology
Peripheral blood mononuclear cell
Medicine
Cancer research

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