Pulmonary hamartomas in Navarra

Introduccion: Pulmonary hamartomas are the most frequent benign pulmonary neoplasms. Methods: A retrospective observational study of all the pulmonary hamartomas diagnosed in our region from 2000 to 2013. Aim: To describe the clinical and epidemiological aspects, as well as the methods used for their diagnosis and treatment. Results: 40 patients were analized;mean age:57 ±10,1 years;60% male and 17% non-smokers. Symptoms at diagnosis: asymptomatics 57,5%, cough 30%, hemoptysis and dyspnea 10% each. The thoracic CT scan described lesions suggestive of hamartoma in 8 cases(20%). The mean radiological size was 1,48cm (range:0,7-5cm). FDG-PET was performed in 15 cases (37,5%);5 cases (12,5%) showed no uptake and the rest of cases had a low SUVmax (mean 1,83; range:0,89 - 3,2). 92% were parenchymatous and 7,5% were endobronchial. 14 cases (35%) presented or had presented one malign neoplasm:5 bronchopulmonary carcinomas (3 adenocarcinomas and 2 squamous cell carcinomas) and 9 extrathoracic carcinomas (3 melanomas, breast, endometrial, liver, testicle, renal and 1 carcinoma of unknown origin). 97,5% of hamartomas were resected. The most frequent surgical procedure was enucleation (47,5%). Conclusions: 1. More than half of patients were asymptomatics at diagnosis. 2. Only 20% of our cases showed evidence in the CT scan suggesting Hamartoma. 3. Most of hamartomas presented as intraparenchymatous solitary lesions. 4. The third part of our patients with hamartomas also had the diagnosis of neoplasms, mainly of extrapulmonary location.