Smart, biocompatible, responsive surfaces on pH, temperature and ionic strength of titanium oxide and niobium oxide with polymer brushes of poly(acrylic acid), poly(N-isopropylacrylamide) and poly([2-(methacryloyloxy)ethyl] trimethylammonium chloride)

Abstract Titanium and Niobium oxide are metallic surfaces used as biomaterials due to their biocompatibility. Their improvement is very important in order to create smart surfaces in terms of responsiveness, with polymer brushes that have a switchable behavior in external stimulus of pH, temperature and ionic strength. The combination with poly(acrylic acid) - PAA, Poly( N -isopropylacrylamide) - PNiPAM and Poly([2-(methacryloyloxy)ethyl] trimethylammonium chloride) – PMETAC polymer brushes as long as their evaluation in biocompatibility and adhesion with cells can lead to smart surfaces that can be used as biomaterials.