Inhibition of 3β-hydroxysteroid dehydrogenase by abiraterone: A rationale for increasing drug exposure in castration-resistant prostate cancer.

Nima Sharifi,Rui Li,Kristen Evaul,Kamalesh K. Sharma,Richard J. Auchus

Inhibition of 3β-hydroxysteroid dehydrogenase by abiraterone: A rationale for increasing drug exposure in castration-resistant prostate cancer.

2017

Nima Sharifi
Rui Li
Kristen Evaul
Kamalesh K. Sharma
Richard J. Auchus

4645 Background: Treatment with abiraterone acetate (abi) increases the survival of men with castration-resistant prostate cancer (CRPC). Resistance to abi invariably occurs, probably due in part t...

Keywords:

Castration
Pathology
Internal medicine
Abiraterone
Prostate cancer
Abiraterone acetate
Hydroxysteroid dehydrogenase
Oncology
Drug
Medicine
Cancer research
castration resistant

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