Association of baseline health-related quality of life and survival in esophagogastric cancers.

118 Background: Baseline health-related quality of life (HRQL) is a prognostic factor for survival in patients with cancer; however contradictory results have been reported. We studied whether HRQL scores are associated with survival in patients with esophagogastric cancers. Methods: Patients with biopsy proven esophagogastric cancer were recruited prospectively. All were invited to respond the EORTC QLQ-C30 questionnaire. The prognostic role of usual clinical variables and HRQL data was analyzed dividing patients in two groups: 1) palliative intention or 2) curative intention treatments. The Kaplan-Meier and Cox's methods were used for bivariate or multivariate analysis, respectively. Results: A total of 259 cases were included, 99 were woman and 160 male (mean age 54.3). One-hundred thirty-three patients of group one, presented significant association with survival in nine of 15 HRQL scales (p < 0.05). A multivariate model was constructed including basal serum albumin (hazard ratio [HR] 0.48; 95% confid...