Comprehensive protein profiling with iTRAQ-based LC-MS/MS to identify proteins associated with doxorubicin and docetaxel resistance in human breast cancers.

Soo-Chin Lee,J. R. Lim,Tiannan Guo,Andrea Li Ann Wong,Stacey Sze Hui Tan,Wee-Lee Yeo,H Yap,Siu Kwan Sze,Boon Cher Goh

Comprehensive protein profiling with iTRAQ-based LC-MS/MS to identify proteins associated with doxorubicin and docetaxel resistance in human breast cancers.

2010

Soo-Chin Lee
J. R. Lim
Tiannan Guo
Andrea Li Ann Wong
Stacey Sze Hui Tan
Wee-Lee Yeo
H Yap
Siu Kwan Sze
Boon Cher Goh

e13038 Background: Proteins are the actual effectors in cells, and protein profiling of cancers treated with chemotherapy may identify biomarkers that predict drug response. Methods: Breast cancer ...

Keywords:

Protein profiling
Doxorubicin
Liquid chromatography–mass spectrometry
Medicine
Internal medicine
Oncology
Docetaxel
Breast cancer
human breast
lc ms ms
Biomarker (medicine)
Chemotherapy
docetaxel resistance

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