Fluorescence quenching of triazatruxene-based glycocluster induced by peanut agglutinin lectin

Abstract A novel triazatruxene-based fluorescent glycocluster was synthesized and its selective binding interactions with PNA lectin were investigated by fluorescence spectroscopy, CD spectroscopy, and a turbidity assay. The glycocluster exhibited a strong binding affinity for PNA lectin with a Stern–Volmer quenching constant of 5.8 × 10 5  mol −1  L.