Fluorescence kinetics of Foscan, Fospeg and Foslip in the window-chamber model

Introduction Foslip and Fospeg are new formulations of the photosensitzer m-THPC, intended for use in Photodynamic Therapy (PDT) of malignancies. Foslip is m-THPC bound to conventional liposomes, Fospeg consists of m-THPC bound to pegylated liposomes. Possible differences in tumour-fluorescence and vasculature kinetics between Foslip, Fospeg and Foscan were studied using the rat window-chamber model.