Extracellular vesicles versus synthetic nanoparticles for drug delivery

Cell-released biological nanoparticles, that is, extracellular vesicles (EVs), are emerging drug carriers with high complexity. EV-based drug delivery exploits intrinsic mechanisms for molecular transport in the body. Integrating EV biology and manufacturing with clinical insights from synthetic nanoparticles is likely to substantially advance the field of drug delivery.