Colonic PDGFRα Overexpression Accompanied Forkhead Transcription Factor FOXO3 Up-Regulation in STZ-Induced Diabetic Mice

Hong Li Lu,Chun-Mei Zhang,Ni-Na Song,Chen Lu,Ling Tong,Xu Huang,Young Chul Kim,Jie Chen,Wen-Xie Xu

Colonic PDGFRα Overexpression Accompanied Forkhead Transcription Factor FOXO3 Up-Regulation in STZ-Induced Diabetic Mice

2017

Hong Li Lu
Chun-Mei Zhang
Ni-Na Song
Chen Lu
Ling Tong
Xu Huang
Young Chul Kim
Jie Chen
Wen-Xie Xu

Background: Colonic transit disorder-induced constipation is a major complication in diabetic patients. PDGFRα+ (platelet-derived growth factor recepto

Keywords:

Transcription factor
FOXO3
Growth factor
Constipation
Diabetes mellitus
Cancer research
Downregulation and upregulation
Biology
PI3K/AKT/mTOR pathway
Akt/PKB signaling pathway
Small hairpin RNA
Growth factor receptor
Platelet-derived growth factor receptor
Cell growth

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