[Advantages of multifactorial analysis of correlations (Benzekri's method) in practice and in clinical research. A simplified example of its application to bladder tumors].

New methodology for the study of treatments of bladder tumors: Multifactorial correlation study according to Benzekri's method. Bladder tumors are characterized by a varying potential for progression which cannot be predicted and which is not taken into consideration in the traditional classification and in the studies concerning efficacy of treatments. The authors propose the attribution of a malignancy coefficient to each bladder tumor. This coefficient is calculated by means of a mathematical method based on statistical correlations (Benzekri method) between 10 prognostic factors, defined prior to any treatment. This coefficient is invariable for each tumor and its correlation with the survival curves has demonstrated its reliability. On the basis of this method, the authors have classified 539 bladder tumors (superficial or invasive) into groups according to their malignancy coefficient. In this way, the ideal treatment for each group can be proposed.