Sarcoidosis-lymphoma syndrome. Presentation of 2 clinical cases

Abstract The combination of sarcoidosis and lymphoma (sarcoidosis-lymphoma syndrome) is a rare but recognized clinical condition. Some manifestations may be common among these conditions, so differentiating each individual disease is challenging for the clinician, and even more so if they coexist in one same patient. In this latter scenario, neither the clinical manifestations, nor the laboratory parameters, are specific; therefore, it is mandatory to do a meticulous analysis of each case, supported by laboratory tests, imaging studies, and histopathology in order to arrive at an accurate diagnosis. This article discusses two cases of sarcoidosis-lymphoma syndrome, with an analysis of the key aspects in the diagnosis of this clinical condition.