Manometric and scintigraphic studies of the relation between motility disturbances in the roux limb and the Roux-en-Y syndrome*

After a Roux-en-Y gastrojejunostomy, patients frequently complain of abdominal pain, fullness, nausea, and vomiting. This so-called Roux-en-Y syndrome is caused by slow gastric emptying, Roux-limb stasis, or both. The pathogenesis of these transit disorders is unknown. The aim of the present study was to investigate whether slow gastric emptying and Roux-limb stasis can be attributed to motility disturbances in the Roux limb. Thirty-seven patients with a Roux-en-Y gastrojejunostomy after partial gastrectomy were studied, 26 of whom had the Roux-en-Y syndrome and 11 who did not. Gastrojejunal transit was evaluated by radionuclide studies, and motility in the Roux limb was studied by manometry. Thirteen patients had slow gastric emptying, and 14 had stasis in the Roux limb. Slow gastric emptying, Roux-limb stasis, or a combination of both was found in 20 of 26 symptomatic patients and in only 4 of 11 asymptomatic patients (p The results of our study indicate that Roux-limb stasis is caused by motility disorders in the Roux limb. They also indicate that Roux-limb stasis is not responsible for slow gastric emptying, since there is no correlation between motility disorders in the Roux limb and slow gastric emptying.