Sickle Cell Anemia Patients in Use of Hydroxyurea: Association between Polymorphisms in Genes Encoding Metabolizing Drug Enzymes and Laboratory Parameters

Sètondji Cocou Modeste Alexandre Yahouédéhou,Magda Oliveira Seixas Carvalho,Rodrigo Mota Oliveira,Rayra Pereira Santiago,Caroline Conceição da Guarda,Suellen Pinheiro Carvalho,Júnia Raquel Dutra Ferreira,Milena Magalhães Aleluia,Elisângela Vitória Adorno,Marilda de Souza Gonçalves

Sickle Cell Anemia Patients in Use of Hydroxyurea: Association between Polymorphisms in Genes Encoding Metabolizing Drug Enzymes and Laboratory Parameters

2018

Sètondji Cocou Modeste Alexandre Yahouédéhou
Magda Oliveira Seixas Carvalho
Rodrigo Mota Oliveira
Rayra Pereira Santiago
Caroline Conceição da Guarda
Suellen Pinheiro Carvalho
Júnia Raquel Dutra Ferreira
Milena Magalhães Aleluia
Elisângela Vitória Adorno
Marilda de Souza Gonçalves

This study investigated associations between SNPs in genes encoding metabolizing drug enzymes and laboratory parameters in sickle cell anemia patients under hydroxyurea (SCA-HU

Keywords:

Genetics
Drug
Diabetes mellitus
Enzyme
Gene
Single-nucleotide polymorphism
Biology
Bioinformatics
Sickle cell anemia
Monocyte
Pharmacology
Lactate dehydrogenase
CYP2E1
Eosinophil
Bilirubin

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