Severe Rhabdomyolysis in a Child With Multisystem Inflammatory Syndrome: An Autoimmune Mechanism?

Coronavirus disease 2019 (COVID-19)–related myositis has been described as an initial presentation and as a potential late complication of COVID-19 in adults.1 In children, rhabdomyolysis has rarely been documented during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,2 , 3 without any detectable alteration in renal function or signs of multiorgan involvement. We here describe the first patient with rhabdomyolysis during multisystem inflammatory syndrome temporally related to COVID-19 (MIS-C).